Circulating MicroRNA: Incident Asthma Prediction and Vitamin D Effect Modification
نویسندگان
چکیده
منابع مشابه
Corticosteroid use and bone mineral accretion in children with asthma: effect modification by vitamin D.
BACKGROUND The adverse effects of corticosteroids on bone mineral accretion (BMA) have been well documented. Vitamin D insufficiency, a prevalent condition in the pediatric population, has also been associated with decreased bone mineral density (BMD). OBJECTIVE We sought to determine whether children with asthma who have lower vitamin D levels are more susceptible to the negative effects of ...
متن کاملVitamin D and asthma
Asthma, one of the most prevalent diseases affecting people worldwide, is a chronic respiratory disease characterized by heightened airway inflammation, airway hyperresponsiveness and airflow obstruction in response to specific triggers. While the specific mechanisms responsible for asthma are not well understood, changing environmental factors associated with urban lifestyles may underlie the ...
متن کاملVitamin D in asthma and future perspectives
Humans have the ability to synthesize vitamin D during the action of ultraviolet (UV) radiation upon the skin. Apart from the regulation of calcium and phosphate metabolism, another critical role for vitamin D in immunity and respiratory health has been revealed, since vitamin D receptors have also been found in other body cells. The term "vitamin D insufficiency" has been used to describe low ...
متن کاملVitamin D deficiency and the asthma epidemic.
The enthusiastic editorial by Weiss and Litonjua (Thorax 2007;62:745–6) may have left some readers with the impression that a single cause of the rise in asthma, multiple sclerosis, inflammatory bowel disease and type 1 diabetes in the West has now been discovered, namely vitamin D deficiency, and that primary prevention of asthma and autoimmune disease is just around the corner. Indeed, their ...
متن کاملGlutethimide and circulating 1,25-dihydroxyvitamin D in vitamin D intoxication.
Iqbal and Taylor used glutethimide to treat a patient with vitamin D2 intoxication, reasoning that induction of hepatic microsomal enzymes by the drug would result in more rapid catabolism of vitamin D metabolites. The treatment corrected the hypercalcaemia, and the raised serum total 25-hydroxyvitamin D concentration fell with induction of the enzymes, as indicated by a rise in y-glutamyltrans...
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ژورنال
عنوان ژورنال: Journal of Personalized Medicine
سال: 2021
ISSN: 2075-4426
DOI: 10.3390/jpm11040307